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In light of one of the most polarizing elections happening a few days ago, we introduce some of the biggest science controversies in the past weeks.
Eledon Pharmaceuticals, Inc. (Eledon), is a biotechnology company led by Dr. David-Alexandre C. Gros, its CEO and a 1999 graduate of the Johns Hopkins School of Medicine. Eledon recently announced that two out of the three subjects with Type 1 diabetes treated with Eledon’s drug, tegoprubart, were able to achieve insulin independence after islet cell transplantation between three and six months post-transplant, with the third on the trajectory for insulin independence.
On Tuesday, Nov. 5, as part of the Johns Hopkins Medicine’s Department of Neurology and Neurosurgery Neuroimmunology Seminar Series, Dr. Amber Salter delivered an overview of her ongoing work concerning comorbidities in multiple sclerosis (MS) disease, titled “Examining Associations of Comorbidities in MS Disease-Modifying Therapy Clinical Trial.” Salter is an associate professor of Biostatistics at UT Southwestern Medical Center.
Anna Gilmore is a professor of Public Health, Director of the Tobacco Control Research Group and Co-Director of the Center for 21st Century Public Health at the University of Bath in England. In an interview with The News-Letter, she discussed her work defining the influence of commercial entities on public health — known as commercial determinants of health (CDOH) — and further described the topics of her talk hosted by the Institute for Global Tobacco Control through the Bloomberg School of Public Health on Nov. 6, 2024.
As the leaves continue to change color, scientific research similarly advances with new progress and innovation. Here are some of the recent studies in the fields of biotechnology, health and chemistry.
The Department of Biology hosted Detlef Weigel, director at the Max Planck Institute for Biology Tübingen and member of the National Academy of Sciences, on Friday, Oct. 25. Weigel gave a talk titled "Imperfect plants in an imperfect world,” which explored his research group’s work on genetic variation in the model organism Arabidopsis thaliana.
Becky Zheng, a sophomore majoring in Neuroscience and Chemistry and minoring in Writing Seminars, started doing research in high school and now continues at the School of Medicine. She is currently working in a lab under Dr. Lee J. Martin, who studies the onset of neurodegenerative diseases like Alzheimer’s and amyotrophic lateral sclerosis. In an interview with The News-Letter, Zheng unraveled her research journey and shared how her time at the lab has seeped into her daily life.
Neha Tripathi, a senior studying Molecular and Cellular Biology and Public Health, is currently a member of the Matunis Lab. The lab, located at the School of Medicine, generally focuses on stem cell dynamics and regeneration. During an interview with The News-letter, Tripathi shared information about her research journey and described not only her role but also the greater importance of her research work.
In a buzzing corner of campus, a group of students is pushing the limits of student-led space innovation. The newly established student organization, JHU CubeSat Club (HopSat), is gearing up to launch a nanosatellite powered by passive solar propulsion, with the ambitious goal of deploying the largest solar sail ever sent into space.
A chimera is an organism composed of cells from two or more distinct genotypes. Human-animal chimeras are a budding area of research and involve the introduction and growth of human tissues in an animal. Chimerism research holds great promise in improving the availability of organs for organ transplantation, which is a major issue due to the current severe organ shortage. Initial chimerism studies involved smaller organisms, such as one where researchers attempted to grow a rat pancreas in a mouse.
Let’s dive into the latest in scientific news and explore recent breakthroughs, discoveries and advancements that are shaping our understanding of the world. This week’s column looks into an unanticipated effect of a type 2 diabetes treatment, explores a recent report in the field of public health and dives into updates in ecology.
The Department of Computer Science hosted Tommi Jaakkola, a professor in the Department of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology and the Institute for Data, Systems and Society, on Tuesday, Oct. 15. In his talk, titled “Generative AI for (Molecular) Sciences,” Jaakkola highlighted the advancements in generative artificial intelligence (AI) for molecular science and material design.
We hope that the fall break was a good time to take a rest. Before diving back into the semester, catch up on the newest scientific discoveries!
As fall break looms ahead, let’s take a look at the recent scientific news. In the past week, laureates of the 2024 Nobel Prizes in Chemistry, Physics and Physiology or Medicine have been announced.
The Johns Hopkins Institute for Clinical & Translational Research hosted the 14th annual Henrietta Lacks Memorial Lecture on Oct. 5 to honor the lasting legacy of Henrietta Lacks. Her cells, taken without her consent in 1951 became one of the most important tools in biomedical research, leading to countless breakthroughs in science. However, her story also brings to light the intersection of medical ethics, race and the treatment of marginalized communities in research.
On August 30, 2017, Kymriah became the first gene therapy — a type of treatment that introduces genetic material to an individual’s cells — to be approved by the Food and Drug Administration (FDA). Kymriah is a treatment for individuals with acute lymphoblastic leukemia, and modifies the individual’s T cells, which help the immune system fight off diseases, by inserting a gene that codes for a chimeric antigen receptor (CAR). The newly created CAR T-cells can then recognize and kill the leukemia cells. As of October 2024, there are more than thirty FDA-approved gene therapies, spanning a diverse array of diseases such as certain cancers, hereditary disorders and chronic diseases.
From general AI platforms like ChatGPT to healthcare diagnostic chatbots, the field of human-computer interaction (HCI) research made enormous strides in replicating elements of human behavior to enhance the user experience during human-computer interaction. On Sept. 30th, Michael Bernstein, an associate professor of computer science at Stanford University, presented a talk at the Center for Language and Speech Processing about current efforts to improve behavioral simulations. His talk was titled “Generative Agents: Interactive Simulacra of Human Behavior“ and spotlighted the simulated town, Smallville, which his team worked on.
From Sept. 24 through Sept. 29, Hurricane Helene ravaged the Southeast, causing over 200 casualties and a staggering $250 billion in damages. Millions of Americans were left without power, and the devastation in states like Florida and Georgia was clear — thousands of buildings were flooded or destroyed, and the land the storm ripped through looked like a wasteland.
Here are some of the most groundbreaking developments in science this week, ranging from a novel approach to rejuvenating brain cells using CRISPR, new insights to understand the link between the TET2 gene and cancer, the global impact of species loss and the discovery of single-electron covalent bonds in carbon atoms.
In the midst of the COVID-19 pandemic, there was increased hesitancy about vaccine effectiveness. Social media powered anti-vaccination campaigns and dangerous misinformation. One form of misinformation is deep fakes, which are becoming more prevalent and pose serious concerns for healthcare. Deep fakes are digitally altered videos or images that can use artificial intelligence to manipulate the words of popular figures, such as politicians or health experts, and can exacerbate global health issues like epidemics and pandemics.