By ANDREW JOHNSON
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By ANDREW JOHNSON
By ZACH JAFFE
By JOHN STOLLER and MICHAEL POZO
By SHANE COUGHLIN
With poor communication and ISIS holds, many Hopkins students are worried and frustrated with the financial aid process.
This past weekend marked the 44th anniversary of Spring Fair, a three-day carnival open to both Hopkins students and the public. Many features of the student-run event, including its name, have evolved throughout its history on the Homewood Campus.
Hopkins placed first in graduate programs for public health and education, second for nursing, and third for research medicine, according to the newest U.S. News and World Report rankings published on Tuesday.
Speed walking down the block, I tried to ignore my roaring stomach. My good friend and I had made plans to watch a movie together at The Charles Theatre for weeks, but between an afternoon of window shopping in Harbor East and panicking over a potentially creepy Uber driver, dinner had slipped my mind. Realistically unable to make it through a two-hour movie without nutrition and unimpressed by The Charles Theatre’s dinner options of hot dogs and popcorn, I was paralyzed by uncertainty. Then my friend suggested we try Sofi’s Crepes.
The fountain of youth has been sought after for millennia but has yet remained elusive. Not even Alexander the Great, who searched for it in the third century B.C., could prove successful in his conquest. However, new research has indicated that it is possible to reverse many of the effects of aging simply by engaging in regular aerobic exercise.
The brains of individuals with autism may shed light onto the physiological nature of one of the most common and most deadly forms of brain cancer. Researchers from the Johns Hopkins University School of Medicine have discovered that both autism and glioblastoma seem to have malfunctioning of the same protein: NHE9. Typically, we do not associate autism with brain cancer – they are two different conditions that are not normally linked together. Autism spectrum disorder is a range of complex neurodevelopment issues that are characterized by communication difficulties and impaired social behavior. This psychological disorder is not fatal and is never the direct cause of death in an individual. Certain types of brain cancers, such as glioblastoma, on the other hand, are extremely dangerous and often fatal. Glioblastoma specifically has a notoriously low survival rate of 10 percent five years after being diagnosed. However, researchers from the Johns Hopkins University School of Medicine have discovered a link between these two seemingly unrelated diseases. In a study published in the journal Nature Communications, the authors describe their work on intracellular transportation. Originally, the researchers had been studying the activity of endosomes, the cell’s main method of transportation (think cargo shipping). All human and animal cells use endosomes to transport newly created proteins to specific destinations in the cell and old proteins to be destroyed and recycled. The speed at which the endosomes travel is regulated by the acidity of the fluids inside of the endosome’s membrane. This in turn is mediated by the activity of proton “pumps” that pull protons into the endosomes and proton “leaks” that push protons out of the membrane. There is a delicate balance of activities to keep the acidity inside of the endosome constant. NHE9, the protein that the researchers were interested in, is a proton leak. In autism, NHE9 proteins are defective and do not let the protons efficiently leak out — the mutated protein essentially acts like a plug. With the buildup of protons, the fluids inside the endosome become more acidic, making them race to transport and destroy proteins, causing premature cell protein death. The researchers searched through patient databases to learn more about NHE9, and they discovered data showing that elevated levels of the proton leak are associated with resistance to traditional cancer treatment methods, such as radiation and chemotherapy, in glioblastoma patients. By examining brain tumors from several patients, they were able to discover that cells with high levels of NHE9 grew faster than cells with a lower level. Furthermore, the researchers found that cells with a higher level of NHE9 could travel faster when placed on a surface similar to that of a brain, suggesting a higher possibility for metastasis. They confirmed this hypothesis by transplanting tumor cells with either high or low levels of NHE9 into the brains of mice.
(Hopkins undergraduates only)
The Johns Hopkins News-Letter’s Statement on Recent Remarks from the Hopkins Feminists Organization:
On Sunday, Nov. 2, a sexual assault of a 16-year-old girl at the Sigma Alpha Epsilon (SAE) fraternity house was reported. The next day, the Inter-Fraternity Council (IFC) voted to ban open parties (any party that isn’t a mixer, date party or formal) for the remainder of the semester. However, University officials later expanded the interim ban to include all social activities held at any of the 12 IFC fraternities. The administration informed the IFC on Thursday night, Nov. 6, that this ban would be effective that weekend and would remain in place until an implementation team had met and developed a plan to better ensure student safety at fraternity parties. They did not inform the general student body, though, until Monday in a JHBroadcast email that explained the decision. By then, rumors and misinformation were already spreading, and the first weekend in which the ban was effective had already passed.
Journalist Laura Ling discussed her imprisonment in North Korea and her career in the media for the penultimate Milton S. Eisenhower (MSE) Symposium event of the year in Shriver Hall on Saturday.
Terry Martinez, formerly the interim dean of student affairs at Columbia University, became the Dean of Student Life at Hopkins this fall.
New routes for the Blue Jay Shuttle system are in effect as of Aug. 18.
The first issue of The News-Letter is a special magazine, created just for freshmen. This is your guide to everything Hopkins — everything you need to know about navigating the FFC, surviving college classes, traveling off-campus, understanding every facet of Blue Jay culture and much, much more. Check it out around campus, or read it online here: http://issuu.com/jhunewsletter/docs/the_cover-letter_2014/1